https://www.ncbi.nlm.nih.gov/pubmed/?term=miRNA+regulation
Esim.- ATG12 ja mikroRNA
- The finding that miR378 targets ATG12 indicated that miR378 may have a potential role in autophagy. These findings may provide novel insights into the mechanism of metastasis in cervical cancer and a novel therapeutic target for the treatment of cervical cancer.
- Results show that ATG12 is a downstream effector in MALAT1-mediated autophagy in gastric cancer cells.
- HBV gained access to Atg5-12/16L1 via interaction of its core protein with the Atg12 moiety of the complex. In contrast, subsequent autophagosome maturation and closure events were unnecessary for HBV replication, as evidenced by inhibition of Atg8/LC3 conjugation. Interfering with the HBV/Atg12 cross talk may be a tool for virus control.
- transcriptional activity of ATG12 gene promoter was not significantly affected by other two DNA sequence variants identified in Parkinson's disease patient
- STAT3 and ATG12 are targets of miR-454-3p.
Inga kommentarer:
Skicka en kommentar