Best matches for RGYW motif:
Breakpoints in the ataxia telangiectasia gene arise at the RGYW somatic hypermutation motif.
Bradshaw PS et al. Oncogene.
(2002)
Cutting edge: DGYW/WRCH is a better predictor of mutability at G:C bases in Ig hypermutation than the widely accepted RGYW/WRCY motif and probably reflects a two-step activation-induced cytidine deaminase-triggered process.
Rogozin IB et al. J Immunol.
(2004)
Somatic hypermutation of human immunoglobulin heavy chain genes: targeting of RGYW motifs on both DNA strands.
Dörner T et al. Eur J Immunol.
(1998)
..., the common sequence of C > T mutations corresponded to the so-called AID motif: WRC or WRCY, where W = A/T, R = A/G, and Y = C/T (Fig. 3c)17. In addition, C > T transitions in the IG locus were also enriched in the AID motif (Fig. 3d).
..., the common sequence of C > T mutations corresponded to the so-called AID motif: WRC or WRCY, where W = A/T, R = A/G, and Y = C/T (Fig. 3c)17. In addition, C > T transitions in the IG locus were also enriched in the AID motif (Fig. 3d).
