SOLUSYKLI: ESCRT-III

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onsdag 16 maj 2018

ESCRT-III, CHMP7 (Kr.8p21.3)

CHMP7
https://www.ncbi.nlm.nih.gov/gene/79643

Preferred Names: charged multivesicular body protein 7

Names: CHMP family, member 7; chromatin-modifying protein 7; RAKENNE:( Peptide sequence. ); https://www.ncbi.nlm.nih.gov/protein/NP_001304828.1

ESCRT-III, CHMP6 (Kr.17q25.3), VPS20

CHMP6
https://www.ncbi.nlm.nih.gov/gene/79643

Preferred Names: charged multivesicular body protein 6

Names: chromatin-modifying protein 6; hVps20; vacuolar protein sorting-associated protein 20; RAKENNE; ( Peptidesequence, isoform X1); https://www.ncbi.nlm.nih.gov/protein/XP_005257725.1

ESCRT-III, CHMP5 (Kr.9p13.3), PNAS-2, SNF7DC2, HSPC177, CGI-34, C9orf183, Vps60

CHMP5

https://www.ncbi.nlm.nih.gov/gene/51510

Preferred Names: charged multivesicular body protein 5
Names: SNF7 domain containing 2; SNF7 domain-containing protein 2; apoptosis-related protein PNAS-2; chromatin-modifying protein 5; hVps60; vacuolar protein sorting-associated protein 60

Also known as: Vps60; CGI-34; PNAS-2; C9orf83; HSPC177; SNF7DC2
Summary: CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs).
Expression: Ubiquitous expression in colon (RPKM 33.4), thyroid (RPKM 32.0) and 25 other tissues See more

RAKENNE: (peptidesequence, isoform 2)
https://www.ncbi.nlm.nih.gov/protein/NP_001182465.1

ESCRT-III, CHMP4C, (Kr.8q21.13) , SNF7-3, Shax3, VPS32C

CHMPC4
https://www.ncbi.nlm.nih.gov/gene/92421

Preferred Names: charged multivesicular body protein 4c

Names: SNF7 homolog associated with Alix 3; Snf7 homologue associated with Alix 3; chromatin modifying protein 4C; chromatin-modifying protein 4c; hSnf7-3; hVps32-3; vacuolar protein sorting-associated protein 32-3; vps32-3; RAKENNE (peptide sequence); https://www.ncbi.nlm.nih.gov/protein/NP_689497.1

ESCRT-III, CHMP4B (Kr. 20q11.22), SNF7-2, VPS32B, CTPP3, Shax1,C20orf178

CHMP4B
https://www.ncbi.nlm.nih.gov/gene/128866

Preferred Names: charged multivesicular body protein 4b

Names: SNF7 homolog associated with Alix 1; Snf7 homologue associated with Alix 1; chromatin modifying protein 4B; chromatin-modifying protein 4b; hSnf7-2; hVps32-2; vacuolar protein-sorting-associated protein

Also known as: SNF7; CTPP3; Shax1; CHMP4A; SNF7-2; VPS32B; CTRCT31; Vps32-2; C20orf178; dJ553F4.4
Summary: This gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1. The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP, also known as ALIX), which also functions in the ESCRT pathway. The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding. These polymers are proposed to help generate the luminal vesicles of multivesicular bodies. Mutations in this gene result in autosomal dominant posterior polar cataracts.[provided by RefSeq, Oct 2009]
Expression: Ubiquitous expression in colon (RPKM 76.6), bone marrow (RPKM 71.5) and 25 other tissues See more

RAKENNE: (peptide sequence)

https://www.ncbi.nlm.nih.gov/protein/NP_789782.1

ESCRT-III, CHMP4A (Kr.14q12), VPS32A, HSPC134, SHAX2, SNF7-1

CHMP4A
https://www.ncbi.nlm.nih.gov/gene/29082

Also known as: SNF7; CHMP4; SHAX2; CHMP4B; SNF7-1; VPS32A; HSPC134; VPS32-1; C14orf123

Preferred Names: charged multivesicular body protein 4a

Names: SNF7 homolog associated with Alix-2; Snf7 homologue associated with Alix 2; chromatin modifying protein 4A; vacuolar protein sorting-associated protein 32-1; RAKENNE:; https://www.ncbi.nlm.nih.gov/protein/NP_054888.2

ESCRT-III, CFMP3 (Kr.2p11.2) , VPS24, NEDF, CGI-149

CHMP3
https://www.ncbi.nlm.nih.gov/gene/51652

Preferred Names: charged multivesicular body protein 3

Names: 25.1 protein; CHMP family, member 3; chromatin-modifying protein 3; neuroendocrine differentiation factor; vacuolar protein sorting 24 homolog; vacuolar protein sorting-associated protein 24

Also known as: NEDF; VPS24; CGI-149
Summary: This gene encodes a protein that sorts transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ring finger protein 103 (RNF103) gene. [provided by RefSeq, Nov 2010]
Expression: Ubiquitous expression in esophagus (RPKM 41.6), thyroid (RPKM 40.0) and 25 other tissues See more; Readthrough gene: RNF103-CHMP3, Included gene: RNF103; RAKENNE: isoformi2; https://www.ncbi.nlm.nih.gov/protein/NP_001005753.1

ESCRT-III, CHMP2B (Kr.3p11.2), ALS17, DMT1, VPS2B, VPS2-2, CHMP2.5

CHMP2B
https://www.ncbi.nlm.nih.gov/gene/25978

Also known as: DMT1; ALS17; VPS2B; VPS2-2; CHMP2.5

Preferred Names: charged multivesicular body protein 2b

Names: VPS2 homolog B; chromatin modifying protein 2B; vacuolar protein-sorting-associated protein 2-2; RAKENNE, isoformi2
https://www.ncbi.nlm.nih.gov/protein/NP_001231573.1

ESCRT-III, CHMP2A (Kr.19q13.43), VPS2, VPS2A,BC2,CHMP2

(Sivumennen sanoen: huomaan että tämä tekijä CHMP2A sijaitsee samassa kromosomikohdassa kuin TRIM28 (TIF1B, KAP19).

CHMP2A

https://www.ncbi.nlm.nih.gov/gene/27243

Preferred Names

charged multivesicular body protein 2a

Names

VPS2 homolog A
chromatin modifying protein 2A
putative breast adenocarcinoma marker (32kD)
putative breast adenocarcinoma marker BC-2
vacuolar protein sorting-associated protein 2-1
vps2-1

BC2; BC-2; VPS2; CHMP2; VPS2A

RAKENNE:

https://www.ncbi.nlm.nih.gov/protein/NP_055268.1

ESCRT-III, CHMP1B (Kr.18p11.21) . Vps46B, C18-ORF2,CHMP1.5, hVps46-2

CHMP1B (Kr. 18p11.21)

https://www.ncbi.nlm.nih.gov/gene/57132

Preferred Names: charged multivesicular body protein 1b

Names: chromatin modifying protein 1B; chromatin-modifying protein 1b; vacuolar protein sorting 46-2; vacuolar protein sorting-associated protein 46-2

Vps46B; C10orf2; C18orf2; CHMP1.5; Vps46-2; C18-ORF2; hVps46-2
Summary CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM, Mar 2008]

RAKENNE:
https://www.ncbi.nlm.nih.gov/protein/NP_065145.2

ESCRT-III, CHMP1A (Kr.16q24.3), PCOLN3, VPS46-1

CHMP1A , PCOLN3 (Kr.16q24.3)

Nimet:

Charged Multivesicular body protein 1A

Chromatin Modifying protein 1A

PCH8

PCOLN3, procollagen (typeIII)N-endopeptidase, protein, metallo,1

PRSM1, Putative metallopetidase 33 kDa (1996)

VPS46-1 VPS46A, Vacuolar protein sorting-associated protein 46-1

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