TRIM77 (Kr. 11q14.3) ,(UC, luokittelematon, nuorimpia löydettyjä) TRIM77P https://www.ncbi.nlm.nih.gov/protein/NP_001139634.1
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GenPept
tripartite
motif-containing protein 77 isoform 1 [Homo sapiens]
NCBI Reference Sequence: NP_001139634.1Identical Proteins FASTA Graphics
LOCUS NP_001139634 450 aa linear PRI 02-OCT-2017 DEFINITION tripartite motif-containing protein 77 isoform 1 [Homo sapiens]. ACCESSION NP_001139634 XP_001717796 XP_941394 VERSION NP_001139634.1 DBSOURCE REFSEQ: accession NM_001146162.1 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (residues 1 to 450) AUTHORS Han K, Lou DI and Sawyer SL. TITLE Identification of a genomic reservoir for new TRIM genes in primate genomes JOURNAL PLoS Genet. 7 (12), E1002388 (2011) PUBMED 22144910 REFERENCE 2 (residues 1 to 450) AUTHORS Taylor TD, Noguchi H, Totoki Y, Toyoda A, Kuroki Y, Dewar K, Lloyd C, Itoh T, Takeda T, Kim DW, She X, Barlow KF, Bloom T, Bruford E, Chang JL, Cuomo CA, Eichler E, FitzGerald MG, Jaffe DB, LaButti K, Nicol R, Park HS, Seaman C, Sougnez C, Yang X, Zimmer AR, Zody MC, Birren BW, Nusbaum C, Fujiyama A, Hattori M, Rogers J, Lander ES and Sakaki Y. TITLE Human chromosome 11 DNA sequence and analysis including novel gene identification JOURNAL Nature 440 (7083), 497-500 (2006) PUBMED 16554811 COMMENT VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AP003122.2, JF968446.1 and JF968445.1. On or before Apr 1, 2009 this sequence version replaced XP_941394.1, XP_001717796.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA2149178 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## FEATURES Location/Qualifiers source 1..450 /organism="Homo sapiens" /db_xref="taxon:9606" /chromosome="11" /map="11q14.3" Protein 1..450 /product="tripartite motif-containing protein 77 isoform 1" /note="putative tripartite motif-containing protein 77; putative tripartite motif-containing protein 64D; TRIM77-isoform; tripartite motif containing 77, pseudogene" /calculated_mol_wt=52319 Region 14..57 /region_name="RING" /note="RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162" /db_xref="CDD:238093" Site order(15,18,30,32,35,38,52,55) /site_type="other" /note="cross-brace motif" /db_xref="CDD:238093" Region 285..449 /region_name="SPRY" /note="SPRY domain; cl02614" /db_xref="CDD:295394" CDS 1..450 /gene="TRIM77" /gene_synonym="TRIM77P" /coded_by="NM_001146162.1:1..1353" /note="isoform 1 is encoded by transcript variant 1" /db_xref="CCDS:CCDS60929.1" /db_xref="GeneID:390231" /db_xref="HGNC:HGNC:34228" ORIGIN 1 masaitqcst seltcsictd yltdpvticc ghrfcspclc llwedtltpn ccpvcreisq 61 qmyfkriifa ekqviptres vpcqlsssam licrrhqeik nlicetdrsl lcflcsqspr 121 hathkhymtr eadeyyrkkl liqmksiwkk kqknqrnlnr etniigtwev finlrsmmis 181 aeypkvcqyl reeeqkhves laregriifq qlkrsqtrma kmgillremy eklkemscka 241 dvnlpqdlgd vmkrneflrl ampqpvnpql sawtitgvse rlnffrvyit ldrkicsnhk 301 llfedlrhlq cslddtdmsc nptstqytss wgaqilssgk hywevdvkds cnwviglcre 361 awtkrndmrl dsegiflllc lkvddhfslf stspllphyi prpqgwlgvf ldyecgivsf 421 vnvaqsslic sflsrifyfp lrpfichgsk
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