HCGP39 ihmisen ruston glykoproteiini 39, Kitinaasi , CHI3L1 , YKL-40

https://www.ncbi.nlm.nih.gov/gene/1116HCGP39
https://www.mybiosource.com/prods/ELISA-Kit/Human/cartilage-glycoprotein39-HCgp-39-YKL-40/HCgp-39-YKL-40/datasheet.php?products_id=9315704

2005 , Luonnolllisen  immuniteetin alueen  proteiini.
https://academic.oup.com/intimm/article/17/11/1505/813358

Official Symbol

CHI3L1provided by HGNC

Official Full Name

chitinase 3 like 1provided by HGNC

Primary source

HGNC:HGNC:1932

See related

Ensembl:ENSG00000133048 MIM:601525; Vega:OTTHUMG00000042122

Gene type

protein coding

RefSeq status

REVIEWED

Organism

Homo sapiens

Lineage

Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo

Also known as

GP39; ASRT7; GP-39; YK-40; YKL40; CGP-39; YKL-40; YYL-40; HC-gp39; HCGP-3P; hCGP-39

Summary

Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. The protein is thought to play a role in the process of inflammation and tissue remodeling. [provided by RefSeq, Sep 2009]

Expression

Biased expression in brain (RPKM 100.8), urinary bladder (RPKM 89.5) and 8 other tissues See more

Orthologs mouse all