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onsdag 7 november 2018

MUC12 (7q22.1) , MUC 11

 MUC12  mainitaan myös MUC11 nimellä.
 https://www.ncbi.nlm.nih.gov/protein/NP_001157934.1
 
 
 
 Summary: This gene encodes an integral membrane glycoprotein that
            is a member of the mucin family. Mucins are O-glycosylated proteins
            that play an essential role in forming protective mucous barriers
            on epithelial surfaces and have been implicated in epithelial
            renewal and differentiation. These glycoproteins also play a role
            in intracellular signaling. This protein is expressed on the apical
            membrane surface of epithelial cells that line the mucosal surfaces
            of many different tissues including the colon, pancreas, prostate,
            and uterus. The expression of this gene is downregulated in
            colorectal cancer tissue. [provided by RefSeq, Apr 2017].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            

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