ZBED5, ZBED7, ZBED8, ZBED9 fylogeneettisesti toista haaraa kuin edelliset

 https://www.genenames.org/data/genegroup/#!/group/64
"Buster"- haaran ZBED geenit.

ZBED5, Buster1 ( 11p15.4)  transposonijohdannainen,  Buster1 transposaasin  kaltainen proteiini

 https://www.ncbi.nlm.nih.gov/gene/58486#gene-expression

Official Symbol

ZBED5provided by HGNC

Official Full Name

zinc finger BED-type containing 5provided by HGNC

Also known as

Buster1

Summary

This gene is unusual in that its coding sequence is mostly derived from Charlie-like DNA transposon; however, it does not appear to be an active DNA transposon as it is not flanked by terminal inverted repeats. The encoded protein is conserved among the mammalian Laurasiatheria branch. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2009]

Expression: Ubiquitous expression in lymph node (RPKM 23.1), endometrium (RPKM 21.4) and 25 other tissues See more

Preferred Names

zinc finger BED domain-containing protein 5

Names

transposon-derived Buster1 transposase-like protein

 NM_001143667.2 → NP_001137139.1  zinc finger BED domain-containing protein 5

 Conserved Domains (1) summary

smart00614
Location:117 → 160

ZnF_BED; BED zinc finger

ORIGIN      
        1 miapllcils ynfntfailn vyskltmfct tnslpmdlll kqgslkqeve sfcyqivses
       61 ndqkvgilqs edkqlqpsvs kksegelsrv kfisnsnkit fskkpkrrky desylsfgft
      121 yfgnrdapha qcvlckkils nsslapsklr rhletkhaay kdkdisffkq hldspennkp
      181 ptpkivntdn esateasynv syhialsgea htigellikp cakdvvmrmf deqyskkida
      241 vqlsnstvar rikdlaadie eelvcrlkic dgfslqldes advsglavll vfvryrfnks
      301 ieedlllces lqsnatgeei fncinsfmqk heiewekcvd vcsdasravd gkiaeavtli
      361 kyvapestss hcllyrhala vkimptslkn vldqavqiin yikarphqsr llkilceemg
      421 aqhtalllnt evrwlsrgkv lvrlfelrre llvfmdsafr lsdcltnssw llrlayladi
      481 ftklnevnls mqgknvtvft vfdkmssllr klefwassve eenfdcfptl sdflteinst
      541 vdkdicsaiv qhlrglratl lkyfpvtndn nawvrnpftv tvkpaslvar dyeslidlts
      601 dsqvkqnfse lslndfwssl iqeypsiarr avrvllpfat mhlcetgfsy yaatktkyrk
      661 rldaaphmri rlsnitpnik ricdkktqkh csh
//

Related articles in PubMed

1. Comparative analysis of the recently discovered hAT transposon TcBuster in human cells. Woodard LE, et al. PLoS One, 2012. PMID 23166581, Free PMC Article
2. Interspersed repeats and other mementos of transposable elements in mammalian genomes. Smit AF. Curr Opin Genet Dev, 1999 Dec. PMID 10607616
3. ZBED evolution: repeated utilization of DNA transposons as regulators of diverse host functions. Hayward A, et al. PLoS One, 2013. PMID 23533661, Free PMC Article
4. Genome-scale RNAi screen for host factors required for HIV replication. Zhou H, et al. Cell Host Microbe, 2008 Nov 13. PMID 18976975
5. Functional proteomics mapping of a human signaling pathway. Colland F, et al. Genome Res, 2004 Jul. PMID 15231748, Free PMC Article

See all (12) citations in PubMed

See citations in PubMed for homologs of this gene provided by HomoloGene

 

GeneRIFs: Gene References Into Functions

1. Observational study of gene-disease association. (HuGE Navigator)
2. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

Submit: New GeneRIF Correction

 https://www.ncbi.nlm.nih.gov/pubmed/26838027 
 https://www.ncbi.nlm.nih.gov/pubmed/23166581