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tisdag 2 juli 2019

SENP2 (3q27.2), AXAM2, SMT3IP2

https://www.ncbi.nlm.nih.gov/gene/59343
Official Symbol
SENP2 provided by HGNC
Official Full Name
SUMO specific peptidase 2provided by HGNC
Also known as
AXAM2; SMT3IP2
Summary
SUMO1 (UBL1; MIM 601912) is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1 into the conjugatable form and catalyze the deconjugation of SUMO1-containing species.[supplied by OMIM, Apr 2004]
Expression. Broad expression in testis (RPKM 37.1), brain (RPKM 13.4) and 24 other tissues
Preferred Names
sentrin-specific protease 2
Names
SMT3-specific isopeptidase 2
SUMO1/sentrin/SMT3 specific peptidase 2
SUMO1/sentrin/SMT3 specific protease 2
sentrin (SUMO1) specific peptidase 2
sentrin/SUMO-specific protease SENP2
 .NM_021627.3NP_067640.2  sentrin-specific protease 2
 Nuclear localization signals:  krrr, pakrpr
Nuclear export signal:  lepdlseevsarlrlg 
NR sites: llerl, llqyl
Conserved Domains (1) summary
COG5160
Location:384589
ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]

Related articles in PubMed
GeneRIFs: Gene References Into Functions
 

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