Päivitän tämän luettelon 2025. ammikuun 16 päivä
Deubiquitinating
enzymes (DUBs) are capable of removing ubiquitin (Ub) from protein
substrates and are involved in numerous biological processes
[2, 4]. DUBs can be divided into 7 subfamilies:
ubiquitin C-terminal hydrolase (UCH)[3],
ubiquitin-specific processing protease (UBP or USP) [1],
otubain protease (OUT),
Machado-Joseph disease protease (MJD),
JAB1/MPN/Mov34 metalloenzyme (JAMM) [4],
monocyte chemotactic protein-induced protein (MCPIP)[5]
and
the motif interacting with Ub-containing novel DUB family (MINDY)
[6].
Deubikitinaasit
5 aiemmin tunnettua ryhmää:
Tioliproteaasit:
(1) USP
(2) UCH
(3) OTU
(4) Josephin
Metalloproteaasit
(5) JAMM
Sitten löytyi 2016 aikoihin
tioliproteaasit
(6) MINDY
ja viimeksi 2018
(7) ZUBSP
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