KLHL36 (16q24.1), C16orf44

https://www.ncbi.nlm.nih.gov/gene/79786

Also known as

C16orf44

Expression

Ubiquitous expression in thyroid (RPKM 7.4), testis (RPKM 6.8) and 25 other tissues See more

1. NM_024731.4 → NP_079007.2  kelch-like protein 36 isoform 1
   See identical proteins and their annotated locations for NP_079007.2
   
   Status: VALIDATED

   Description

   Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).

   Source sequence(s)

   AC009116, AK022605, AW337439, BC033821, DA049618

   Consensus CDS

   CCDS10948.1

   UniProtKB/Swiss-Prot

   Q8N4N3

   Related

   ENSP00000456743.1, ENST00000564996.6

   Conserved Domains (6) summary

   smart00612
   Location:547 → 593

   Kelch; Kelch domain

   PHA03098
   Location:45 → 585

   PHA03098; kelch-like protein; Provisional

   sd00038
   Location:335 → 383

   Kelch; KELCH repeat [structural motif]

   pfam00651
   Location:36 → 139

   BTB; BTB/POZ domain

   pfam01344
   Location:386 → 431

   Kelch_1; Kelch motif

   pfam07707
   Location:149 → 250

   BACK; BTB And C-terminal Kelch

ORIGIN      
        1 mmegsrqtrv srpykisess kvyrwadhss tvlqrlneqr lrglfcdvvl vadeqrvpah
       61 rnllavcsdy fnsmftigmr eafqkeveli gasyiglkav vdflyggelv ldggnidyvl
      121 etahllqiwt vvdfcceyle qevsednyly lqelasiysl krldafidgf ilnhfgtlsf
      181 tpdflqnvsm qklcvylsss evqrecehdl lqaalqwltq qpereaharq vlenihfpli
      241 pkndllhrvk pavcsllpke ancegfieea vryhnnlaaq pvmqtkrtal rtnqerllfv
      301 ggevsercle lsddtcylda kseqwvketp lparrshhcv avlggfifia ggsfsrdngg
      361 daasnllyry dprckqwikv asmnqrrvdf ylasiedmlv aiggrnenga lssvetyspk
      421 tdswsyvagl prftyghagt iykdfvyisg ghdyqigpyr knllcydhrt dvweerrpmt
      481 targwhsmcs lgdsiysigg sddniesmer fdvlgveays pqcnqwtrva pllhansesg
      541 vavwegriyi lggyswenta fsktvqvydr eadkwsrgvd lpkaiaggsa cvcaleprpe
      601 dkkkkgkgkr hqdrgq

Rakenteessa kiinnittää huomiota  noin 40 aminohappoparia, joissa on

 samat aminohapot vierekkäin kuten  mm, ss, ll,gg, vv, aa,ee,nn, dd, rr,

 hh, ee, kk