KBTBD6(13q14.11) muodostaa heterotrimeerin KBTBD7 ja CLR3:n kanssa. Sitoo GABARAP

https://www.ncbi.nlm.nih.gov/gene/89890
NM_152903.5 → NP_690867.3  kelch repeat and BTB domain-containing protein 6
See identical proteins and their annotated locations for NP_690867.3

REFERENCE   1  (residues 1 to 674)
  AUTHORS   Genau HM, Huber J, Baschieri F, Akutsu M, Dotsch V, Farhan H, Rogov
            V and Behrends C.
  TITLE     CUL3-KBTBD6/KBTBD7 ubiquitin ligase cooperates with GABARAP
            proteins to spatially restrict TIAM1-RAC1 signaling
  JOURNAL   Mol. Cell 57 (6), 995-1010 (2015)
   PUBMED   25684205
  REMARK    GeneRIF: KBTBD6 and KBTBD7 specifically bind to GABARAP
            proteins.KBTBD6 and KBTBD7 form a heterodimeric CRL3 complex.
REFERENCE   2  (residues 1 to 674)
  AUTHORS   Behrends C, Sowa ME, Gygi SP and Harper JW.
  TITLE     Network organization of the human autophagy system
  JOURNAL   Nature 466 (7302), 68-76 (2010)
   PUBMED   20562859

 

1. NM_152903.5 → NP_690867.3  kelch repeat and BTB domain-containing protein 6
   See identical proteins and their annotated locations for NP_690867.3
   

   ORIGIN      
           1 mqsredaprs rrlasprggk rpkkihkptv safftgpeel kdtahsaall aqlksfydar
          61 llcdvtievv tpgsgpgtgr lfpcnrnvla aacpyfksmf tggmyesqqa svtmhdvdae
         121 sfevlvdycy tgrvslsean verlyaasdm lqleyvreac asflarrldl tnctailkfa
         181 dafghrklrs qaqsyiaqnf kqlshmgsir eetladltla qllavlrlds ldveseqtvc
         241 hvavqwleaa pkergpsaae vfkcvrwmhf teedqdyleg lltkpivkky cldviegalq
         301 mrygdllyks lvpvpnssss ssssnslvsa aenppqrlgm cakemviffg hprdpflccd
         361 pysgdlykvp spltclahtr tvttlavcis pdhdiylaaq prtdlwvykp aqnswqqlad
         421 rllcregmdv aylngyiyil GGrdpitgvk lkevecYnvk rnqWalvapl phsflsfdlm
         481 virdylyaln skrmfcydps hnmwlkcvsl krndfqeacv fneeiycicd ipvmkvynpv
         541 raewrqmnni plvsetnnyr iikhGGklll itsrtpqWkk nrvtvYeYdi rgdqWinigt
         601 tlgllqfdsn ffclsarvyp sclepgqsfl teeeeipses stewdlGGfs epdsesgsss
         661 slsdddfwvr vapq

   Conserved Domains (2) summary

   sd00038
   Location:425 → 471

   Kelch; KELCH repeat [structural motif]

   cl28614
   Location:55 → 553

   BTB; Broad-Complex, Tramtrack and Bric a brac

https://www.sciencedirect.com/science/article/pii/S1097276514010181

https://marlin-prod.literatumonline.com/cms/attachment/6450de6a-5936-4482-baf6-024a218a8e3e/fx1.jpg

 https://ars.els-cdn.com/content/image/1-s2.0-S1097276514010181-fx1.jpg