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måndag 4 mars 2019

Plexiineistä PLXNA1 (3q21.3)

 Plexiin A1 on muilta nimiltään
Semaforiinireseptorio NOV,
 NOVP,
 PLEXIN-A1,
PLXN1.
Se ilmenee keuhkossa, testiksessä, aivossa ja 23 muussa kudoksessa.

 https://www.ncbi.nlm.nih.gov/gene/5361

 Plexiini A1 prekursoripeptidi 1896 aminohappoa 

https://www.ncbi.nlm.nih.gov/protein/NP_115618.3

PlexiiniA1-peptidin konservatiiviset domeenit:

Conserved Domains (7) summary
cd11271
Location:38513
Sema_plexin_A1; The Sema domain, a protein interacting module, of Plexin A1
cd01179
Location:9611046
IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
cd01180
Location:864960
IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
cd01181
Location:10481148
IPT_plexin_repeat3; Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
pfam01437
Location:514556
PSI; Plexin repeat
pfam01833
Location:11501234
TIG; IPT/TIG domain
pfam08337
Location:13181866
Plexin_cytopl; Plexin cytoplasmic RasGAP domain

Related articles in PubMed

https://www.sciencedirect.com/science/article/pii/S1742706115302014?via%3Dihub#f0030

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

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