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måndag 24 april 2017

INFRAÄÄNI aiheena

Ihminen ei tavallesti kuule äänenä  20 Hz  alla olevia  frekvenssejä., mutta keho  voi muulla tavalla havaita tätäkin  infraääniaaltoaluetta.
ESIMERKKEJÄ:
      • Tuulivoimaloiden infraääni

J Acoust Soc Am. 2015 Mar;137(3):1356-65. Doi: 10.1121/1.4913775.
A theory to explain some physiological effects of the infrasonic emissions at some wind farm sites.
Abstract
For at least four decades, there have been reports in scientific literature of people experiencing motion sickness-like symptoms attributed to low-frequency sound and infrasound. In the last several years, there have been an increasing number of such reports with respect to wind turbines; this corresponds to wind turbines becoming more prevalent. A study in Shirley, WI, has led to interesting findings that include: (1) To induce major effects, it appears that the source must be at a very low frequency, about 0.8 Hz and below with maximum effects at about 0.2 Hz; (2) the largest, newest wind turbines are moving down in frequency into this range; (3) the symptoms of motion sickness and wind turbine acoustic emissions "sickness" are very similar; (4) and it appears that the same organs in the inner ear, the otoliths may be central to both conditions. Given that the same organs may produce the same symptoms, one explanation is that the wind turbine acoustic emissions may, in fact, induce motion sickness in those prone to this affliction.
PMID:
25786948
DOI:
10.1121/1.4913775


  • Kuulokynnys
Matalan frekvenssin ja infraäänialueen frekvenssien kuulemisen kynnysrajaa on luodattu vaopaaehtoisilta tähän tarkoitukseen kehitetyllä menetelmällä Jaksolukualue 2 Hz- 125 Hz saadaan havaittua. Tällaista aliteta voidaan käyttää stimuksen kalibroimiseen enen aivokuvaustutkimuksia.
J Acoust Soc Am. 2015 Apr;137(4):EL347-53. doi: 10.1121/1.4916795.

Infrasonic and low-frequency insert earphone hearing threshold.
Abstract
Low-frequency and infrasonic pure-tone monaural hearing threshold data down to 2.5 Hz are presented. These measurements were made by means of a newly developed insert-earphone source. The source is able to generate pure-tone sound pressure levels up to 130 dB between 2 and 250 Hz with very low harmonic distortions. Behavioral hearing thresholds were determined in the frequency range from 2.5 to 125 Hz for 18 otologically normal test persons. The median hearing thresholds are comparable to values given in the literature. They are intended for stimulus calibration in subsequent brain imaging investigations.
PMID:
25920888
DOI:
[Indexed for MEDLINE]
 
      • Millä neurokemiallisella tavalla infraääni vaikuttaa haittaa  hermokudoksessa?

Excitotoksinen vaikutus korreloi glutamaatin vapautumiseen (konneksiini hemikanavan Cx43 kautta ) astrogliasta ja kliinisesti tätä aivotoksisuutta on oppimiskyvyn ja muistin huononema.
Neurochem Res. 2014 May;39(5):833-42. doi: 10.1007/s11064-014-1277-3. Epub 2014 Mar 15.Involvement of connexin43 in the infrasonic noise-induced glutamate release by cultured astrocytes. Jiang S1, Wang YQ, Xu CF, Li YN, Guo R, Li L.
Abstract
Infrasonic noise/infrasound is a type of environmental noise that threatens public health as a nonspecific biological stressor. Glutamate-related excitotoxicity is thought to be responsible for infrasound-induced impairment of learning and memory. In addition to neurons, astrocytes are also capable of releasing glutamate. In the present study, to identify the effect of infrasound on astroglial glutamate release, cultured astrocytes were exposed to infrasound at 16 Hz, 130 dB for different times. We found that infrasound exposure caused a significant increase in glutamate levels in the extracellular fluid. Moreover, blocking the connexin43 (Cx43) hemichannel or gap junction, decreasing the probability of Cx43 being open or inhibiting of Cx43 expression blocked this increase. The results suggest that glutamate release by Cx43 hemichannels/gap junctions is involved in the response of cultured astrocytes to infrasound.
PMID:
24634254 
 
  • Aivojen plastisuudelle olennainen lipidien vaihtuminen häiriintyy ,
 Aivothan ovat rasvamoduli, joka  uudistaa lipidejään 20 %  n. viikossa vauhdilla ja tässä järjestelmässä toimivat mm ne  arakidonihappoperäiset  johdannaiset ( "endokannabinoidit2) ja siihen järjestelmään tarvitaan essentiellejä  rsahappoja (linoli, linoleeni  EPA, DHA ovat näitä tunnettuja essentiellejä rasvahappoja) ).
 
[Indexed for MEDLINE] Acta Biochim Biophys Sin (Shanghai). 2015 Aug;47(8):647-53. doi: 10.1093/abbs/gmv049. Epub 2015 Jun 9.
Involvement of cannabinoid receptors in infrasonic noise-induced neuronal impairment.
Ma L1, He H2, Liu X1, Zhang G1, Li L1, Yan S3, Li K4, Shi M5.
Abstract
Excessive exposure to infrasound, a kind of low-frequency but high-intensity sound noise generated by heavy transportations and machineries, can cause vibroacoustic disease which is a progressive and systemic disease, and finally results in the dysfunction of central nervous system. Our previous studies have demonstrated that glial cell-mediated inflammation may contribute to infrasound-induced neuronal impairment, but the underlying mechanisms are not fully understood. Here, we show that cannabinoid (CB) receptors may be involved in infrasound-induced neuronal injury. After exposure to infrasound at 16 Hz and 130 dB for 1-14 days, the expression of CB receptors in rat hippocampi was gradually but significantly decreased. Their expression levels reached the minimum after 7- to 14-day exposure during which the maximum number of apoptotic cells was observed in the CA1. 2-Arachidonoylglycerol (2-AG), an endogenous agonist for CB receptors, reduced the number of infrasound-triggered apoptotic cells, which, however, could be further increased by CB receptor antagonist AM251. In animal behavior performance test, 2-AG ameliorated the infrasound-impaired learning and memory abilities of rats, whereas AM251 aggravated the infrasound-impaired learning and memory abilities of rats. Furthermore, the levels of proinflammatory cytokines tumor necrosis factor alpha and interleukin-1β in the CA1 were upregulated after infrasound exposure, which were attenuated by 2-AG but further increased by AM251. Thus, our results provide the first evidence that CB receptors may be involved in infrasound-induced neuronal impairment possibly by affecting the release of proinflammatory cytokines.
© The Author 2015. Published by ABBS Editorial Office in association with Oxford University Press on behalf of the Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences.
KEYWORDS: cannabinoid receptors; infrasound; neuronal impairment; proinflammatory cytokines; vibroacoustic disease


Infraääni ja near infrasound frequences näyttää olevan  muutamille helppoa käsittää
https://www.youtube.com/watch?v=_ytAq9sOXMo


Tästä endokannabinoidikartasta olen kirjoittanut molekyylejä muistiin rasvahappoblogiini, joten viittaan näihin vanhoihin muisiinpanoihin:koska nyt sain tietää endokanabinoidiresedptorin  "uudesta" stimulaattorista infraäänestä, joka pitää ottaa ilemsiesti huomioon  työsuojelussa koneitten  suhteen eräänlaisena  infraäänipitoisuuden   suositeltuna korkeinpana raja-arvona- tietty  nämä oavt olemassa, kun ne vain hakee esiin.  Moni infraääni lähde on man made ja kuuluu viimeisiin nykyaikaisiin lisiin miljöössä.


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