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torsdag 19 april 2018

TRIM77 (Kr.11q15.4) , luokitetlematon TRIM77P( pseudogeeni?)

TRIM77 (Kr. 11q14.3) ,(UC, luokittelematon, nuorimpia löydettyjä) TRIM77P https://www.ncbi.nlm.nih.gov/protein/NP_001139634.1

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GenPept
tripartite motif-containing protein 77 isoform 1 [Homo sapiens]
NCBI Reference Sequence: NP_001139634.1
Identical Proteins FASTA Graphics



LOCUS       NP_001139634             450 aa            linear   PRI 02-OCT-2017
DEFINITION  tripartite motif-containing protein 77 isoform 1 [Homo sapiens].
ACCESSION   NP_001139634 XP_001717796 XP_941394
VERSION     NP_001139634.1
DBSOURCE    REFSEQ: accession NM_001146162.1
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 450)
  AUTHORS   Han K, Lou DI and Sawyer SL.
  TITLE     Identification of a genomic reservoir for new TRIM genes in primate
            genomes
  JOURNAL   PLoS Genet. 7 (12), E1002388 (2011)
   PUBMED   22144910
REFERENCE   2  (residues 1 to 450)
  AUTHORS   Taylor TD, Noguchi H, Totoki Y, Toyoda A, Kuroki Y, Dewar K, Lloyd
            C, Itoh T, Takeda T, Kim DW, She X, Barlow KF, Bloom T, Bruford E,
            Chang JL, Cuomo CA, Eichler E, FitzGerald MG, Jaffe DB, LaButti K,
            Nicol R, Park HS, Seaman C, Sougnez C, Yang X, Zimmer AR, Zody MC,
            Birren BW, Nusbaum C, Fujiyama A, Hattori M, Rogers J, Lander ES
            and Sakaki Y.
  TITLE     Human chromosome 11 DNA sequence and analysis including novel gene
            identification
  JOURNAL   Nature 440 (7083), 497-500 (2006)
   PUBMED   16554811
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AP003122.2, JF968446.1 and JF968445.1.
            On or before Apr 1, 2009 this sequence version replaced
            XP_941394.1, XP_001717796.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            transcript and genomic sequence to make the sequence consistent
            with the reference genome assembly. The genomic coordinates used
            for the transcript record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed/partial sample support SAMEA2149178
                              [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..450
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q14.3"
     Protein         1..450
                     /product="tripartite motif-containing protein 77 isoform
                     1"
                     /note="putative tripartite motif-containing protein 77;
                     putative tripartite motif-containing protein 64D;
                     TRIM77-isoform; tripartite motif containing 77,
                     pseudogene"
                     /calculated_mol_wt=52319
     Region          14..57
                     /region_name="RING"
                     /note="RING-finger (Really Interesting New Gene) domain, a
                     specialized type of Zn-finger of 40 to 60 residues that
                     binds two atoms of zinc; defined by the 'cross-brace'
                     motif C-X2-C-X(9-39)-C-X(1-3)-
                     H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved
                     in...; cd00162"
                     /db_xref="CDD:238093"
     Site            order(15,18,30,32,35,38,52,55)
                     /site_type="other"
                     /note="cross-brace motif"
                     /db_xref="CDD:238093"
     Region          285..449
                     /region_name="SPRY"
                     /note="SPRY domain; cl02614"
                     /db_xref="CDD:295394"
     CDS             1..450
                     /gene="TRIM77"
                     /gene_synonym="TRIM77P"
                     /coded_by="NM_001146162.1:1..1353"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS60929.1"
                     /db_xref="GeneID:390231"
                     /db_xref="HGNC:HGNC:34228"
ORIGIN      
        1 masaitqcst seltcsictd yltdpvticc ghrfcspclc llwedtltpn ccpvcreisq
       61 qmyfkriifa ekqviptres vpcqlsssam licrrhqeik nlicetdrsl lcflcsqspr
      121 hathkhymtr eadeyyrkkl liqmksiwkk kqknqrnlnr etniigtwev finlrsmmis
      181 aeypkvcqyl reeeqkhves laregriifq qlkrsqtrma kmgillremy eklkemscka
      241 dvnlpqdlgd vmkrneflrl ampqpvnpql sawtitgvse rlnffrvyit ldrkicsnhk
      301 llfedlrhlq cslddtdmsc nptstqytss wgaqilssgk hywevdvkds cnwviglcre
      361 awtkrndmrl dsegiflllc lkvddhfslf stspllphyi prpqgwlgvf ldyecgivsf
      421 vnvaqsslic sflsrifyfp lrpfichgsk

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