KCTD14 (11q14.19) ilmentyy lisämunuaisesa ja mahalaukussa. Kartoituksen alainen KCTD

https://www.ncbi.nlm.nih.gov/gene/65987

Official Symbol

KCTD14

Official Full Name

potassium channel tetramerization domain containing 14provided by HGNC

Expression

Broad expression in adrenal (RPKM 10.1), stomach (RPKM 9.5) and 17 other tissues See more

Related articles in PubMed

1. A proteome-scale map of the human interactome network. Rolland T, et al. Cell, 2014 Nov 20. PMID 25416956, Free PMC Article
2. The BioPlex Network: A Systematic Exploration of the Human Interactome. Huttlin EL, et al. Cell, 2015 Jul 16. PMID 26186194, Free PMC Article ( tämä on karakterisointia)
3. Architecture of the human interactome defines protein communities and disease networks. Huttlin EL, et al. Nature, 2017 May 25. PMID 28514442, Free PMC Article
4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

See all (6) citations in PubMed

BTB/POZ domain-containing protein KCTD14 isoform 1 [Homo sapiens]

NCBI Reference Sequence: NP_076419.2

Identical Proteins FASTA Graphics

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LOCUS       NP_076419                255 aa            linear   PRI 02-MAY-2019
DEFINITION  BTB/POZ domain-containing protein KCTD14 isoform 1 [Homo sapiens].
ACCESSION   NP_076419
VERSION     NP_076419.2
DBSOURCE    REFSEQ: accession NM_023930.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
           ..
REFERENCE   1  (residues 1 to 255)
  AUTHORS   Rolland T, Tasan M, et al. 
  TITLE     A proteome-scale map of the human interactome network
  JOURNAL   Cell 159 (5), 1212-1226 (2014)
   PUBMED   25416956
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AP003032.2, CB993622.1, BC001929.1 and BU631809.1.
            On Apr 6, 2007 this sequence version replaced NP_076419.1.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR3476690.88534.1,
                                           SRR3476690.497039.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2162841 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000353172.6/ ENSP00000316482.5
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..255
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q14.1"
     Protein         1..255
                     /product="BTB/POZ domain-containing protein KCTD14 isoform
                     1"
                     /note="BTB/POZ domain-containing protein KCTD14; potassium
                     channel tetramerisation domain containing 14"
                     /calculated_mol_wt=29460
     Region          35..125
                     /region_name="BTB"
                     /note="Broad-Complex, Tramtrack and Bric a brac;
                     smart00225"
                     /db_xref="CDD:197585"
     Region          35..118
                     /region_name="BTB"
                     /note="BTB/POZ domain; cl02518"
                     /db_xref="CDD:295341"
     CDS             1..255
                     /gene="KCTD14"
                     /coded_by="NM_023930.4:28..795"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS8255.2"
                     /db_xref="GeneID:65987"
                     /db_xref="HGNC:HGNC:23295"
ORIGIN      
        1 mwqgcaverp vgrmtsqtpl pqsprprrpt mstvvelnvg gefhtttlgt lrkfpgskla
       61 emfsslakas tdaegrffid rpstyfrpil dylrtgqvpt qhipevyrea qfyeikplvk
      121 lledmpqifg eqvsrkqfll qvpgysenle lmvrlaraea itarkssvlv clveteeqda
      181 yysevlcflq dkkmfksvvk fgpwkavldn sdlmhclemd ikaqgykvfs kfyltyptkr
      241 nefhfniysf tftww
//

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