S100B merkkiaineena syövässä

 https://pubmed.ncbi.nlm.nih.gov/29345293/

. Our results revealed that a high S100B expression predicted a good overall survival in patients with ER-negative breast cancer, and good distant metastases-free survival in all patients with breast cancer via the analysis of the KM plotter and SurvExpress databases. Although previous studies have indicated that the interaction of S100B with wild-type p53 inhibits p53 function, a high S100B expression is associated with a good prognosis in patients with p53 mutant and p53 wild-type breast cancers. On the whole, our findings demonstrate that S100B treatment suppresses the migratory capacity of ER-negative breast cancer and that S100B expression may serve a predictive marker for metastasis in breast cancer. 

 

S100B and S100B autoantibody as biomarkers for early detection of brain metastases in lung cancer.

Choi H, Puvenna V, Brennan C, Mahmoud S, Wang XF, Phillips M, Janigro D, Mazzone P. Transl Lung Cancer Res. 2016 Aug;5(4):413-9. doi: 10.21037/tlcr.2016.07.08. PMID: 27652205 Free PMC article.

We explored the use of serum S100B protein and S100B autoantibodies for the detection of brain metastasis in patients with lung cancer. ...CONCLUSIONS: Serum S100B and S100B autoantibody levels may help to identify which lung cancer patie …