https://en.wikipedia.org/wiki/BTB/POZ_domain
The BTB/POZ domain is a common structural domain contained within some proteins.
The BTB (for BR-C, ttk and bab)[2] or POZ (for Pox virus and Zinc finger)[3] domain is present near the N-terminus of a fraction of zinc finger proteins and in proteins that contain the Kelch motif
and a family of pox virus proteins
The BTB/POZ domain mediates
homomeric dimerisation and in some instances heteromeric dimerisation.[3]
The structure of the dimerised PLZF BTB/POZ domain has been solved and
consists of a tightly intertwined homodimer. The central scaffolding of
the protein is made up of a cluster of alpha-helices flanked by short
beta-sheets at both the top and bottom of the molecule.[1]
BTB/POZ domains from several zinc finger proteins have been shown to
mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT.[4][5][6]
The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
https://www.researchgate.net/publication/235371825_Structural_Basis_for_Cul3_Protein_Assembly_with_the_BTB-Kelch_Family_of_E3_Ubiquitin_Ligases
https://www.researchgate.net/publication/235371825_Structural_Basis_for_Cul3_Protein_Assembly_with_the_BTB-Kelch_Family_of_E3_Ubiquitin_Ligases
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