https://www.ncbi.nlm.nih.gov/gene/?term=KLHL39
- Official
Symbol
- IVNS1ABPprovided by HGNC
- Official
Full Name
- influenza virus NS1A binding protein provided by HGNC
- Also known as
- ND1; ARA3; NS-1; NS1BP; FLARA3; KLHL39; NS1-BP; HSPC068
- Expression
- Ubiquitous expression in bone marrow (RPKM 56.1), kidney (RPKM 31.5) and 24 other tissues See more
- Orthologs mouse
all
-
- Preferred Names
- influenza virus NS1A-binding protein
- Names
- NCX downstream gene 1
- NS1-binding protein
- aryl hydrocarbon receptor-associated 3
- aryl hydrocarbon receptor-associated protein 3
- kelch-like family member 39
- kelch-like protein 39
-
-
NM_006469.5 → NP_006460.2 influenza virus NS1A-binding protein
See identical proteins and their annotated locations for NP_006460.2
Status: VALIDATED
- Source sequence(s)
- AB020657, AF205218, AK000931, AL137640
- Consensus CDS
- CCDS1368.1
- UniProtKB/Swiss-Prot
- Q9Y6Y0
- Related
- ENSP00000356468.3, ENST00000367498.8
- Conserved Domains (2) summary
-
- sd00038
Location:502 → 545
- Kelch; KELCH repeat [structural motif]
- cl28614
Location:23 → 638
- BTB; Broad-Complex, Tramtrack and Bric a brac
-
FEATURES Location/Qualifiers
source 1..642
/organism="Homo sapiens"
/db_xref="taxon:9606"
/chromosome="1"
/map="1q25.3"
Protein 1..642
/product="influenza virus NS1A-binding protein"
/note="NS1-binding protein; NCX downstream gene 1; aryl
hydrocarbon receptor-associated 3; aryl hydrocarbon
receptor-associated protein 3; kelch-like family member
39; kelch-like protein 39"
/calculated_mol_wt=71599
Region 23..638
/region_name="BTB"
/note="Broad-Complex, Tramtrack and Bric a brac; cl28614"
/db_xref="CDD:333434"
Region 164..368
/region_name="Sufficient for AHR interaction and
signaling"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9Y6Y0.3)"
Site 246
/site_type="phosphorylation"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine. {ECO:0000244|PubMed:19690332};
propagated from UniProtKB/Swiss-Prot (Q9Y6Y0.3)"
Site 277
/site_type="phosphorylation"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine. {ECO:0000244|PubMed:16964243};
propagated from UniProtKB/Swiss-Prot (Q9Y6Y0.3)"
Site 322
/site_type="phosphorylation"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine. {ECO:0000244|PubMed:16964243};
propagated from UniProtKB/Swiss-Prot (Q9Y6Y0.3)"
Site 336
/site_type="phosphorylation"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine. {ECO:0000244|PubMed:18691976};
propagated from UniProtKB/Swiss-Prot (Q9Y6Y0.3)"
Site 338
/site_type="phosphorylation"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine. {ECO:0000244|PubMed:18669648,
ECO:0000244|PubMed:18691976, ECO:0000244|PubMed:23186163};
propagated from UniProtKB/Swiss-Prot (Q9Y6Y0.3)"
Region 358..401
/region_name="KELCH repeat"
/note="KELCH repeat [structural motif]"
/db_xref="CDD:276965"
Region 369..415
/region_name="Kelch 1"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9Y6Y0.3)"
Region 409..451
/region_name="KELCH repeat"
/note="KELCH repeat [structural motif]"
/db_xref="CDD:276965"
Region 416..463
/region_name="Kelch 2"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9Y6Y0.3)"
Region 453..498
/region_name="KELCH repeat"
/note="KELCH repeat [structural motif]"
/db_xref="CDD:276965"
Region 465..512
/region_name="Kelch 3"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9Y6Y0.3)"
Region 502..545
/region_name="KELCH repeat"
/note="KELCH repeat [structural motif]"
/db_xref="CDD:276965"
Region 513..559
/region_name="Kelch 4"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9Y6Y0.3)"
Region 549..593
/region_name="KELCH repeat"
/note="KELCH repeat [structural motif]"
/db_xref="CDD:276965"
Region 560..606
/region_name="Kelch 5"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9Y6Y0.3)"
Region 596..635
/region_name="KELCH repeat"
/note="KELCH repeat [structural motif]"
/db_xref="CDD:276965"
Region 608..642
/region_name="Kelch 6"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9Y6Y0.3)"
CDS 1..642
/gene="IVNS1ABP"
/gene_synonym="ARA3; FLARA3; HSPC068; KLHL39; ND1; NS-1;
NS1-BP; NS1BP"
/coded_by="NM_006469.5:538..2466"
/db_xref="CCDS:CCDS1368.1"
/db_xref="GeneID:10625"
/db_xref="HGNC:HGNC:16951"
/db_xref="MIM:609209"
ORIGIN
1 mipngylmfe denfiessva klnalrksgq fcdvrlqvcg hemlahravl accspylfei
61 fnsdsdphgi shvkfddlnp eavevllnya ytaqlkadke lvkdvysaak klkmdrvkqv
121 cgdyllsrmd vtscisyrnf ascmgdsrll nkvdayiqeh llqiseeeef lklprlklev
181 mlednvclps ngklytkvin wvqrsiweng dsleelmeev qtlyysadhk lldgnlldgq
241 aevfgsdddh iqfvqkkppr enghkqisss stgclsspna tvqspkhewk ivasektsnn
301 tylclavldg ifcviflhgr nspqssptst pklskslsfe mqqdeliekp mspmqyarsg
361 lgtaemngkl iaaggynree clrtvecynp htdhwsflap mrtprarfqm avlmgqlyvv
421 ggsnghsddl scgemydsni ddwipvpelr tnrcnagvca lngklyivgg sdpygqkglk
481 ncdvfdpvtk lwtscaplni rrhqsavcel ggylyiigga eswnclntve rynpenntwt
541 liapmnvarr gagvavlngk lfvcggfdgs haiscvemyd ptrnewkmmg nmtsprsnag
601 iatvgntiya vggfdgnefl ntvevynles newspytkif qf
//
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658946/figure/F1/
Inga kommentarer:
Skicka en kommentar