Kevät 2020. ZDHHC sinkkisormiryhmä on proteiini- palmityylitransferaaseja !

Olin etsimässä  koronaviruksen palmitylaation tausta tekijöitä ja  sitten  törmäsintähän sinkkisormiryjhmään ZDHHC.
 https://www.genenames.org/data/genegroup/#!/group/76

Gene group: Zinc fingers DHHC-type (ZDHHC)

Also known as : "zf-DHHC", "DHHC palmitoyltransferase domain containing", "Protein acyl transferases", "PATs", "Palmitoyltransferases", "DHHC-type acyltransferases"

A subgroup of : "Zinc fingers"

Genes contained within the group: 24

HGNC ID (gene)	Approved symbol	Approved name	Previous symbols	Aliases	Chromosome
HGNC:17916	ZDHHC1	zinc finger DHHC-type containing 1	C16orf1	HSU90653,ZNF377	16q22.1
HGNC:18469	ZDHHC2	zinc finger DHHC-type palmitoyltransferase 2		ZNF372,DHHC2	8p22
HGNC:18470	ZDHHC3	zinc finger DHHC-type palmitoyltransferase 3		ZNF373,GODZ,DHHC3	3p21.31
HGNC:18471	ZDHHC4	zinc finger DHHC-type palmitoyltransferase 4		FLJ10479,ZNF374	7p22.1
HGNC:18472	ZDHHC5	zinc finger DHHC-type palmitoyltransferase 5 (* SARS-2 S-protein interaction)		KIAA1748,ZNF375,DHHC5	11q12.1
HGNC:19160	ZDHHC6	zinc finger DHHC-type palmitoyltransferase 6		ZNF376,FLJ21952	10q25.2
HGNC:18459	ZDHHC7	zinc finger DHHC-type palmitoyltransferase 7		FLJ10792,ZNF370,FLJ20279,SERZ-B,SERZ1,DHHC7	16q24.1
HGNC:18474	ZDHHC8	zinc finger DHHC-type palmitoyltransferase 8		ZNF378,KIAA1292	22q11.21
HGNC:18475	ZDHHC9	zinc finger DHHC-type palmitoyltransferase 9	ZDHHC10,CXorf11	ZNF379,CGI-89,ZNF380,DHHC9	Xq26.1
HGNC:19158	ZDHHC11	zinc finger DHHC-type containing 11		ZNF399,FLJ13153	5p15.33
HGNC:32962	ZDHHC11B	zinc finger DHHC-type containing 11B			5p15.33
HGNC:19159	ZDHHC12	zinc finger DHHC-type palmitoyltransferase 12		ZNF400,FLJ14524	9q34.11
HGNC:18413	ZDHHC13	zinc finger DHHC-type palmitoyltransferase 13		FLJ10852,FLJ10941,HIP14L	11p15.1
HGNC:20341	ZDHHC14	zinc finger DHHC-type palmitoyltransferase 14		FLJ20984,NEW1CP	6q25.3
HGNC:20342	ZDHHC15	zinc finger DHHC-type palmitoyltransferase 15		FLJ31812,MRX91,DHHC15	Xq13.3
HGNC:20714	ZDHHC16	zinc finger DHHC-type palmitoyltransferase 16		APH2	10q24.1
HGNC:18412	ZDHHC17	zinc finger DHHC-type palmitoyltransferase 17		HIP14,HYPH,KIAA0946	12q21.2
HGNC:20712	ZDHHC18	zinc finger DHHC-type palmitoyltransferase 18		DKFZp667O2416	1p36.11
HGNC:20713	ZDHHC19	zinc finger DHHC-type palmitoyltransferase 19		MGC33345	3q29
HGNC:20749	ZDHHC20	zinc finger DHHC-type palmitoyltransferase 20		FLJ25952,DHHC20	13q12.11
HGNC:20750	ZDHHC21	zinc finger DHHC-type palmitoyltransferase 21		HSPC097,DNZ1,DHHC21	9p22.3
HGNC:20106	ZDHHC22	zinc finger DHHC-type palmitoyltransferase 22	C14orf59		14q24.3
HGNC:28654	ZDHHC23	zinc finger DHHC-type palmitoyltransferase 23		MGC42530	3q13.31
HGNC:27387	ZDHHC24	zinc finger DHHC-type containing 24			11q13.2

Specialist advisors

Dr Susan Gentleman

Publications

Protein palmitoylation: Palmitoyltransferases and their specificity.

Tabaczar S et al. Exp. Biol. Med. (Maywood) 2017 Jun;242(11)1150-1157

PMID: 28485685 Europe PMC, Pubmed

The DHHC domain: a new highly conserved cysteine-rich motif.

Putilina T et al. Mol. Cell. Biochem. 1999 May;195(1-2)219-226

PMID: 10395086 Europe PMC, Pubmed

11.2. 2020  "Uutta viruksista" -blogissani  etsin asioita koronaviruksesta , lähinnä nCoV ja SARS CoV.  ja siinä yhteydessä luin palmitylaatiosta artikkelin:  Artikkeli maintisee koronaviruksetkin yleisnimeltä.

  https://www.frontiersin.org/articles/10.3389/fimmu.2017.02003/full

Review ARTICLE

Front. Immunol., 19 January 2018 | https://doi.org/10.3389/fimmu.2017.02003

Protein Palmitoylation and Its Role in Bacterial and Viral Infections

Justyna Sobocińska, Paula Roszczenko-Jasińska, Anna Ciesielska and Katarzyna Kwiatkowska*

• Laboratory of Molecular Membrane Biology, Department of Cell Biology, Nencki Institute of Experimental Biology of the Polish Academy of Sciences, Warsaw, Poland