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onsdag 3 juni 2015

Calretikuliiniproteiini

                     /db_xref="MIM:109091"
ORIGIN      
        1 mllsvplllg llglavaepa vyfkeqfldg dgwtsrwies khksdfgkfv lssgkfygde
       61 ekdkglqtsq darfyalsas fepfsnkgqt lvvqftvkhe qnidcgggyv klfpnsldqt
      121 dmhgdseyni mfgpdicgpg tkkvhvifny kgknvlinkd irckddefth lytlivrpdn
      181 tyevkidnsq vesgsleddw dflppkkikd pdaskpedwd erakiddptd skpedwdkpe
      241 hipdpdakkp edwdeemdge weppviqnpe ykgewkprqi dnpdykgtwi hpeidnpeys
      301 pdpsiyaydn fgvlgldlwq vksgtifdnf litndeayae efgnetwgvt kaaekqmkdk
      361 qdeeqrlkee eedkkrkeee eaedkedded kdedeedeed keedeeedvp gqakdel
//
 
 
                      /map="19p13.3-p13.2"
     Protein         1..417
                     /product="calreticulin precursor"
                     /note="Sicca syndrome antigen A (autoantigen Ro;
                     calreticulin); CRP55; ERp60; HACBP; grp60; calregulin;
                     endoplasmic reticulum resident protein 60; epididymis
                     secretory sperm binding protein Li 99n"
 signal_peptide     1..17
                     /inference="COORDINATES: ab initio prediction:SignalP:4.0"
                     /calculated_mol_wt=1693
     mature _peptide     18..417
                     /product="calreticulin"
                     /calculated_mol_wt=46467 
 
  Region          191..255
                     /region_name="4 X approximate repeats"
                     /experiment="experimental evidence, no additional details
                     recorded"
 
    Region          259..297
                     /region_name="3 X approximate repeats"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (P27797.1)"
 
 
 Region          414..417 (kdel) 
                     /region_name="Prevents secretion from ER" 

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